As of today, the cumulative number of detected COVID-19 cases is 661 936 with 725 new cases identified.
| Province | Total cases for 21 September 2020 | Percentage total |
| Eastern Cape | 88 205 | 13,3 |
| Free State | 44 291 | 6,7 |
| Gauteng | 217 485 | 32,9 |
| KwaZulu-Natal | 117 833 | 17,8 |
| Limpopo | 14 721 | 2,2 |
| Mpumalanga | 26 525 | 4,0 |
| North West | 28 187 | 4,3 |
| Northern Cape | 15 163 | 2,3 |
| Western Cape | 109 526 | 16,5 |
| Unknown | 0 | 0,0 |
| Total | 661 936 | 100,0 |
The cumulative number of tests conducted to date is 4 047 723 with 725 new tests conducted since the last report.
| Sector | Total tested | New tested | ||
| PRIVATE | 2 293 138 | 57% | 1 266 | 20% |
| PUBLIC | 1 754 585 | 43% | 4 914 | 80% |
| Total | 4 047 723 | 6 180 |
Total Deaths and Recoveries
Regrettably, we report 39 more COVID-19 related deaths: 9 from Eastern Cape, 1 from KwaZulu-Natal, 9 from Gauteng, 16 from North West and 4 from Western Cape. This brings the total number of COVID-19 related deaths to 15 992.
We extend our condolences to the loved ones of the departed and thank the heal- care workers that treated the deceased patients.
Our recoveries now stand at 591 208 which translates to a recovery rate of 89,3%
| Province | Total Deaths | Total Recoveries | Active Cases |
| Eastern Cape | 3 079 | 84 108 | 1018 |
| Free State | 838 | 29 093 | 14 360 |
| Gauteng | 4 039 | 193 429 | 20 017 |
| KwaZulu-Natal | 2 532 | 108 063 | 7 238 |
| Limpopo | 362 | 13 756 | 603 |
| Mpumalanga | 496 | 25 156 | 873 |
| North West | 341 | 24 101 | 3745 |
| Northern Cape | 184 | 11 541 | 3438 |
| Western Cape | 4 121 | 101 961 | 3 444 |
| National | 15 992 | 591 208 | 54 736 |